Non-stinging BENADRYL Itch Relief Spray contains a topical antihistamine/analgesic and a skin protectant to provide fast, effective relief at the source from itchiness and pain due to allergic reactions, poison ivy, insect bites, mild sunburn or skin irritations. Symptom Relief Provides fast, effective relief of skin itch and pain caused by: Allergic reactions Poison Ivy, Oak, Sumac Insect bites/stings Mild sunburn Minor skin irritations, cuts or scrapes